| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8475391 | Journal of Molecular and Cellular Cardiology | 2013 | 10 Pages |
Abstract
⺠In cardiomyocytes low concentrations of CT-1 impair stimulation of glucose uptake. ⺠Low CT-1 activates STAT5, increases SOCS3 and reduces GLUT4. ⺠STAT5 inhibition restores glucose uptake, insulin signaling and GLUT4 expression. ⺠High concentrations of CT-1 increase basal and stimulated glucose uptake. ⺠High CT-1 activates AMPK in a CaMKII-dependent manner.
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Authors
Mohamed Asrih, Stéphany Gardier, Irène Papageorgiou, Christophe Montessuit,