Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8475395 | Journal of Molecular and Cellular Cardiology | 2013 | 13 Pages |
Abstract
⺠Haptoglobin deficiency impairs microvascular integrity after infarction. ⺠Haptoglobin prevents heme-induced oxidative stress and regulates VEGF/angiopoietin-1 balance. ⺠Haptoglobin deficiency impairs wound healing and proper scar formation after MI. ⺠Haptoglobin deficiency worsens both short- and longterm cardiac function and geometry.
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Authors
Fatih Arslan, Mirjam B. Smeets, Brigitta Buttari, Elisabetta Profumo, Rachele Riganò, Lars Akeroyd, Emrah Kara, Leo Timmers, Joost P. Sluijter, Ben van Middelaar, Krista den Ouden, Gerard Pasterkamp, Sai Kiang Lim, Dominique P.V. de Kleijn,