| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8475413 | Journal of Molecular and Cellular Cardiology | 2013 | 11 Pages |
Abstract
⺠Mitochondrial ROS mediate adrenergic adaption in pathological cardiac hypertrophy. ⺠Cardiac adaptation is associated with preserved mitochondrial biogenesis. ⺠Decreased mitochondrial bioenergetics accompanies the transition to cardiac failure. ⺠Bioenergetic failure is mediated by sustained adrenergic-induced cAMP-PKA pathway.
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Authors
Mariana G. Rosca, Bernard Tandler, Charles L. Hoppel,