| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8475417 | Journal of Molecular and Cellular Cardiology | 2013 | 8 Pages |
Abstract
⺠Mitochondrial Ca2 + activates Krebs cycle enzymes to adapt energy supply to demand. ⺠Close association of mitochondria to SR establishes a Ca2 + microdomain. ⺠Mitofusin 2, but not mitofusin 1 tethers mitochondria to the SR in cardiac myocytes. ⺠Impaired mitochondrial Ca2 + uptake causes energetic mismatch and oxidative stress.
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Authors
Gerald W. II, Christoph Maack,