Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8475428 | Journal of Molecular and Cellular Cardiology | 2013 | 9 Pages |
Abstract
⺠Physiological concentration of glutamine is marginally anaplerotic in the heart. ⺠Glutamine's primary metabolic effect is to increase fatty acid oxidation and storage. ⺠These effects of glutamine involve CD36 and the hexosamine biosynthetic pathway (HBP). ⺠The HBP represents a new mechanism for the acute regulation of cardiac metabolism.
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Authors
Benjamin Lauzier, Fanny Vaillant, Clemence Merlen, Roselle Gélinas, Bertrand Bouchard, Marie-Eve Rivard, Francois Labarthe, Vern W. Dolinsky, Jason R.B. Dyck, Bruce G. Allen, John C. Chatham, Christine Des Rosiers,