| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8475456 | Journal of Molecular and Cellular Cardiology | 2011 | 11 Pages |
Abstract
⺠Angiotensin-II induces cardiomyocyte hypertrophy in vitro via AT1 and WISP1. ⺠AT1 physically associates with NOX2. ⺠Angiotensin-II activates TCF/LEF via superoxide/Akt/GSK3β/β-catenin. ⺠Angiotensin-II activates CREB via Akt and superoxide-mediated p38MAPK and ERK1/2 activation. ⺠Angiotensin-II induced myocardial hypertrophy in vivo is associated with WISP1 upregulation.
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Authors
Prakashsrinivasan Shanmugam, Anthony J. Valente, Sumanth D. Prabhu, Balachandar Venkatesan, Tadashi Yoshida, Patrice Delafontaine, Bysani Chandrasekar,