Article ID Journal Published Year Pages File Type
8475474 Journal of Molecular and Cellular Cardiology 2011 12 Pages PDF
Abstract
► Nogo-A is up-regulated following hypoxic/ischemic injury. ► Nogo-A knockdown protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis. ► Nogo-A knockdown inhibits ΔΨm dissipation, ROS generation, cytochrome c release, and abnormal Ca2+ cycling.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
Nogo-A knockdown inhibits hypoxia/reoxygenation-induced activation of mitochondrial-dependent apoptosis in cardiomyocytes
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