Early postnatal development of the visual cortex in mice with retinal degeneration

The findings of this study provide a snapshot of the dynamic changes in cortex formation during early postnatal development. So far, it is the first investigation on the postnatal development of the mouse visual cortex. Our results indicate that in C3H/HeNRj mice retinal degeneration during these early stages may not influence the maturation of the visual cortex. Until P28 in this mouse strain, the development of the visual neocortex is in accordance with data from other mice (C57BL/6) without retinal degeneration. Whether in older individuals of the C3H/HeNRj strain the visual neocortex will show signs of functional impairment has to be shown by future work.