Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8476110 | Mechanisms of Development | 2013 | 11 Pages |
Abstract
⺠In Drosophila mesoderm invagination, ventral cells constrict their apical surfaces. ⺠Heterotrimetic G protein signaling is required for apical constriction. ⺠We found that G protein is also required for the organisation of cortical actin. ⺠Disruption of cortical actin induced membrane blebbing during apical constriction. ⺠G protein confers physical stability on the cell surface during morphogenesis.
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Authors
Takuma Kanesaki, Susumu Hirose, Joerg Grosshans, Naoyuki Fuse,