Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8476111 | Mechanisms of Development | 2013 | 17 Pages |
Abstract
⺠Dlk1flox mice were generated to allow conditional deletion of the Dlk1 gene. ⺠Dlk1cons null mutants display perinatal death and reduced growth of survivors. ⺠Increased cellularity of Dlk1cons placentae may limit maternal-fetal exchange. ⺠Loss of Dlk1 in beta cells, somatotropes or endothelial cells causes no pathology.
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Authors
Oliver K. Appelbe, Aleksey Yevtodiyenko, Hilmarie Muniz-Talavera, Jennifer V. Schmidt,