Article ID Journal Published Year Pages File Type
8476117 Mechanisms of Development 2013 12 Pages PDF
Abstract
► Fetal liver was separated into hepatoblasts, endothelial cells and hematopoietic cells by flow cytometry. ► Extracellular matrix genes and proteins were expressed primarily by DLK-1-expressing hepatoblasts. ► Matrix production was down-regulated in Map2k4−/− fetal liver, which lacks hepatoblasts. ► Hepatoblasts expressed TGF-beta receptor type-2. ► ECM production in hepatoblasts is controlled by TGF-beta-1.
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