| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8476156 | Mechanisms of Development | 2012 | 15 Pages |
Abstract
⺠We examined the role of the TRAP enzyme during endochondral bone formation in mice. ⺠TRAP does not impair vascularization as well as ossification of the long bone epiphysis. ⺠TRAPâ/â mice show an expansion of the cartilaginous growth plate. ⺠This malformation is first detected at week three and during further development. ⺠TRAP appears to be critical for the formation of the metaphysis but not of the epiphysis.
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Authors
Michael J.F. Blumer, Barbara Hausott, Christoph Schwarzer, Alison R. Hayman, Judith Stempel, Helga Fritsch,