Article ID Journal Published Year Pages File Type
8476172 Mechanisms of Development 2012 14 Pages PDF
Abstract
► We identified EflMsiA as the first sponge stem cell (archeocyte)-specific gene. ► EflMsiA protein is predominantly localized in the nucleus in interphase archeocytes. ► M-phase archeocytes with high EflMsiA expression are probably self-renewing. ► M-phase archeocytes with low EflMsiA expression might be differentiating. ► Symmetric cell division of archeocytes is strongly suggested.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
The active stem cell specific expression of sponge Musashi homolog EflMsiA suggests its involvement in maintaining the stem cell state
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