| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8476204 | Mechanisms of Development | 2012 | 15 Pages |
Abstract
⺠Undifferentiated spermatogonia differentiate periodically in mouse seminiferous tubules. ⺠Meiotic and haploid germ cells regulate the local retinoic acid (RA) metabolism. ⺠The increased RA triggers the differentiation of undifferentiated spermatogonia. ⺠RA also resets the functional cycle of somatic Sertoli cells. ⺠Thus, RA metabolism links the germ cell differentiation and Sertoli cell cycle.
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Authors
Ryo Sugimoto, Yo-ichi Nabeshima, Shosei Yoshida,