Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8476947 | Molecular and Cellular Endocrinology | 2015 | 11 Pages |
Abstract
FetA can promote lipotoxicity in β cells through the TLR4-JNK-NF-κB signaling pathway. The protective effects of PIO on lipotoxicity in β cells may involve the inhibition of the activation of the FetA and TLR4 signaling pathway.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Ximei Shen, Liyong Yang, Sunjie Yan, Huanhuan Zheng, Liyu Liang, Xiuhui Cai, Meng Liao,