Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8476990 | Molecular and Cellular Endocrinology | 2015 | 11 Pages |
Abstract
- In vivo blockade of testicular α1-ADRs reduces circulating androgen level.
- α1-ADR blockade abolished stress-induced partial recovery of androgen production.
- α1-ADRs mediate stress-reduced steroidogenic stimulator Nur77 in Leydig cells.
- α1-ADRs mediate stress-increased repressors Dax1 and Arr19 in Leydig cells.
- α1-ADRs on Leydig cell regulate transcription of steroidogenic stimulator Nur77.
Keywords
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Authors
Natasa J. Stojkov-Mimic, Maja M. Bjelic, Sava M. Radovic, Aleksandar I. Mihajlovic, Srdjan J. Sokanovic, Aleksandar Z. Baburski, Marija M. Janjic, Tatjana S. Kostic, Silvana A. Andric,