Article ID Journal Published Year Pages File Type
8477369 Molecular and Cellular Endocrinology 2013 10 Pages PDF
Abstract
► Dusp6 was over-expressed in human endometrial adenocarcinomas. ► Dusp6 expression blocked FGF2-induced ERK1/2 signaling activity in Ishikawa cells. ► Dusp6 expression significantly enhanced the growth of Ishikawa cells. ► Dusp6 expression sensitized Ishikawa cells to 17β-estradiol-induced cell growth.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
Dual-specificity phosphatase 6 (Dusp6), a negative regulator of FGF2/ERK1/2 signaling, enhances 17β-estrodial-induced cell growth in endometrial adenocarcinoma cell
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