| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477487 | Molecular and Cellular Endocrinology | 2013 | 6 Pages |
Abstract
⺠We demonstrated that STARD5 specifically binds bile acids but not cholesterol. ⺠The binding site of STARD5 has been experimentally defined. ⺠The ligand binding by STARD1, STARD5 and STARD6 was monitored by NMR. ⺠We compare the binding site of STARD5 with those of STARD1 and STARD4 subfamilies. ⺠The potential biological implications of bile acid binding by STARD5 are discussed.
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Authors
Danny Létourneau, Andrée Lefebvre, Pierre Lavigne, Jean-Guy LeHoux,