Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8477499 | Molecular and Cellular Endocrinology | 2013 | 15 Pages |
Abstract
⺠'Non-classical' StAR facilitates steroidogenesis or other mitochondrial activities. ⺠Steroidogenic StAR affects development and protects against cytotoxic insults. ⺠In transformed cells, steroidogenic StAR allows escape from tumor immunity. ⺠StAR can enhance bile acid production and synthesis of regulatory oxysterols. ⺠StAR can also confer anti-apoptotic robustness and chemotherapy resistance.
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Authors
Eli Anuka, Michael Gal, Douglas M. Stocco, Joseph Orly,