Article ID Journal Published Year Pages File Type
8477499 Molecular and Cellular Endocrinology 2013 15 Pages PDF
Abstract
► 'Non-classical' StAR facilitates steroidogenesis or other mitochondrial activities. ► Steroidogenic StAR affects development and protects against cytotoxic insults. ► In transformed cells, steroidogenic StAR allows escape from tumor immunity. ► StAR can enhance bile acid production and synthesis of regulatory oxysterols. ► StAR can also confer anti-apoptotic robustness and chemotherapy resistance.
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