Article ID Journal Published Year Pages File Type
8477503 Molecular and Cellular Endocrinology 2013 9 Pages PDF
Abstract
► Basal and stress-induced adrenal glucocorticoid secretion are episodic. ► Episodic secretion parallels episodes of steroidogenic protein gene transcription. ► ACTH mediates ultradian and stress-induced transcriptional episodes. ► Nuclear localization of the co-activator, TORC, precedes transcriptional activation. ► TORC regulation may play a key role in transcriptional pulse generation.
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