| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477504 | Molecular and Cellular Endocrinology | 2013 | 8 Pages |
Abstract
⺠Lipoxygenated metabolites of arachidonic acid stimulate StAR protein induction. ⺠The role of OXE-R, a leukotriene receptor, in the stimulation of steroidogenesis was determined. ⺠OXE-R was detected in human adrenocortical H295R cells. ⺠An antagonist of the OXE-R inhibits StAR protein induction and steroidogenesis. ⺠The prototypical OXE-R agonist 5-oxo-ETE increases cAMP-dependent StAR induction and steroidogenesis.
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Authors
Mariana Cooke, Hernán Di Cónsoli, Paula Maloberti, Fabiana Cornejo Maciel,