| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477534 | Molecular and Cellular Endocrinology | 2013 | 8 Pages |
Abstract
⺠hCG promotes MKP-3 gene transcription in MA-10 Leydig cells via PKA and ERK. ⺠hCG up-regulates MKP-3 at post-translational level in MA-10 Leydig cells. ⺠cAMP induces a transient increase in p21 mRNA levels in MA-10 cells. ⺠The cAMP-dependent increase in p21 mRNA levels is modulated by MKP-3 expression.
Keywords
nESshRNAGAPDHGnRHL19FOXO1FGFSTAR geneDAPIMKP-3LHRMKPDUSPsP214′,6-diamidino-2-phenylindoleERK1/2MAP kinase phosphataseMAPKMAPK phosphataseMEK1/2p-ERK1/2short hairpin RNADual specificity phosphatasesreverse transcriptionLeydig cellsfibroblast growth factorphospho-Erk1/2gonadotropin releasing hormoneluteinizing hormoneForkhead box protein O1Steroidogenic acute regulatory proteinStar proteinmitogen-activated protein kinaseglyceraldehyde-3-phosphate dehydrogenaseLuteinizing hormone receptor
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Authors
Mercedes Mori Sequeiros GarcÃa, Natalia V. Gómez, Alejandra Gorostizaga, Andrea Acquier, Silvia I. González-Calvar, Carlos F. Mendez, Cristina Paz,