| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477545 | Molecular and Cellular Endocrinology | 2013 | 7 Pages |
Abstract
⺠LC-MS/MS measures several steroids in one experiment on a single small sample. ⺠Pre-analytical extraction prevents instrument contamination and ion suppression. ⺠The sensitivity of LC-MS/MS assays varies for different structural classes of steroids. ⺠Derivatization improves sensitivity, particularly for specific types of steroids.
Keywords
MSNUPLCMRMMTBEAPPILTQCDCAPCICIDESICRPCLC-MS/MSCollision-induced dissociationSteroidEnzyme-linked immunosorbent assayELISACastration-resistant prostate cancerMass spectrometryAdrenal glandsRadio frequencymethyl tert-Butyl etherCenter for Disease ControlPathwaysmultiple reaction monitoringCongenital adrenal hyperplasiaultra performance liquid chromatographyhigh performance liquid chromatographyliquid chromatography–tandem mass spectrometryHPLCGas chromatographyelectrospray ionizationchemical ionizationatmospheric pressure chemical ionization
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Authors
Kerry M. Wooding, Richard J. Auchus,