| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477548 | Molecular and Cellular Endocrinology | 2013 | 7 Pages |
Abstract
⺠Somatic KCNJ5 mutations occur in up to 40% of APA. ⺠KCNJ5 mutations lead to activation of calcium signaling and increased aldosterone production. ⺠Adrenals with APA display increased nodulation, reduced vascularization and zona glomerulosa hyperplasia. ⺠Presence of KCNJ5 mutations is not correlated with adrenal cortex remodeling.
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Authors
Sheerazed Boulkroun, José-Felipe Golib Dzib, Benoit Samson-Couterie, Fabio Luiz Fernandes Rosa, Amanda Jane Rickard, Tchao Meatchi, Laurence Amar, Arndt Benecke, Maria-Christina Zennaro,