Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8477583 | Molecular and Cellular Endocrinology | 2013 | 7 Pages |
Abstract
⺠Hyperglycemia frequently develops during acute stroke. ⺠We model cerebral ischemia to study the mechanisms of hyperglycemia. ⺠Hepatic expression of gluconeogenic genes and transcription factors is increased. ⺠Insulin resistance develops in liver with elevated glucagon and inflammation. ⺠Enhanced hepatic gluconeogenesis contributes to post-stroke hyperglycemia.
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Authors
Ya-Yu Wang, Chun-Jung Chen, Shih-Yi Lin, Yu-Han Chuang, Wayne Huey-Herng Sheu, Kwong-Chung Tung,