| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477588 | Molecular and Cellular Endocrinology | 2013 | 39 Pages |
Abstract
⺠Expression of CYP1A1, CYP3A7, COMT and MB-COMT levels were higher in endometriosis. ⺠Expression of SULT1E1, SULT2B1, UGT2B7, NQO1, and GSTP1 was decreased. ⺠Three NQO1 isoforms were detected; NQO1c appears to be endometriosis-specific. ⺠This imbalance between phase I and II enzymes may lead to excessive ROS formation. ⺠Hydroxy-estrogens and ROS can promote proliferation of ovarian endometriotic cells.
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Authors
Neli Hevir, Martina RibiÄ-Pucelj, Tea LaniÅ¡nik Rižner,