| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477602 | Molecular and Cellular Endocrinology | 2012 | 10 Pages |
Abstract
⺠Expression of STX1A, SYT4, SYT7, SYT11 and SYT13 is reduced in islets from human T2D donors. ⺠Expression of STX1A, SYT4, SYT7, SYT11, SYT13, SNAP25 and STXBP1 correlates positively with GSIS. ⺠Expression of STX1A, SYT4, SYT7, SYT11, SYT13, SNAP25 and STXBP1 correlates negatively to HbA1c. ⺠Reduced expression of exocytotic genes contribute to impaired insulin secretion.
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Authors
Sofia A. Andersson, Anders H. Olsson, Jonathan L.S. Esguerra, Emilia Heimann, Claes Ladenvall, Anna Edlund, Albert Salehi, Jalal Taneera, Eva Degerman, Leif Groop, Charlotte Ling, Lena Eliasson,