Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8477615 | Molecular and Cellular Endocrinology | 2012 | 13 Pages |
Abstract
⺠Cortisol stimulates Na+ uptake and ammonia excretion in zebrafish larvae through glucocorticoid receptor. ⺠The stimulation of Na+ uptake in larvae during acid-exposure is at least partially mediated by increased cortisol level. ⺠Cortisol stimulates Na+ uptake by stimulating the recently proposed NHE3b-Rhcg1 functional metabolon. ⺠Glucocorticoid receptor is highly expressed in ionocytes responsible for Na+ uptake.
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Authors
Yusuke Kumai, Dinushan Nesan, Mathilakath M. Vijayan, Steve F. Perry,