Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8477633 | Molecular and Cellular Endocrinology | 2012 | 9 Pages |
Abstract
⺠The transcription factor c-Myb interacts with the glucocorticoid receptor (GR). ⺠The knockdown of c-Myb reduces the levels of GR transcripts and protein. ⺠The knockdown of c-Myb lowers the levels of GR promoter 1C and 1D transcripts. ⺠The knockdown of c-Myb blunts the autoupregulation of GR promoters 1C and 1D. ⺠Reduced c-Myb levels, by itself, decreases cell viability.
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Authors
Purvaba J. Sarvaiya, Jason R. Schwartz, Chuan-dong Geng, Wayne V. Vedeckis,