Article ID Journal Published Year Pages File Type
8477638 Molecular and Cellular Endocrinology 2012 12 Pages PDF
Abstract
► Insulin and resveratrol acts synergistically for osteoblast differentiation. ► The osteoblast differentiation is mediated through Sirt1-dependent pathway. ► Sirt1 decreases adipocyte formation. ► Phosporylated Akt stabilizes β-catenin in the nucleus.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
Synergistic actions of insulin-sensitive and Sirt1-mediated pathways in the differentiation of mouse embryonic stem cells to osteoblast
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