| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477661 | Molecular and Cellular Endocrinology | 2012 | 13 Pages |
Abstract
⺠Endogenous androgens have long been considered to be risk factors for prostate cancer. ⺠Increasing data suggest that PCa develops through a variety of interconnected genes, some of which belong to the androgen pathway. ⺠New genomic biomarkers will likely make it possible to better estimate the risk of PCa, and distinguish indolent disease from aggressive. ⺠This data may become important for targeted screening and chemoprevention programs.
Keywords
UGTDHEAHsd3bAKR1C3SULT17β-Hydroxysteroid dehydrogenaseSHBGSRD5A2dehydroepiandrosteroneNGSCyPPSADHTCNV3α-hydroxysteroid dehydrogenasePCAProstate specific antigencopy number variationNext generation sequencingRiskProstate cancersulfotransferaseCytochrome P450Cancer etiologyMIMUTR یا untranslated regions untranslated regionMendelian Inheritance in Manluteinizing hormonesex hormone binding globulinVariantPolymorphismSingle nucleotide polymorphismSNPAndrogen Receptor
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Authors
Johanna Schleutker,