Article ID Journal Published Year Pages File Type
8477662 Molecular and Cellular Endocrinology 2012 6 Pages PDF
Abstract
► Overexpression of androgen receptor transforms the androgen-dependent growth to independent one. ► Amplification of AR gene is found in 30% of castration-resistant prostate cancers. ► Tumors treated with antiandrogens show missense mutations. ► AR splice variant are found in castration-resistant prostate cancers.
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