| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477666 | Molecular and Cellular Endocrinology | 2012 | 7 Pages |
Abstract
⺠Interleukin-6 is a multifunctional cytokine which regulates growth of prostate cancer. ⺠Stimulation of androgen receptor activity by interleukin-6 may enhance or inhibit proliferation. ⺠Interleukin-6 inhibits apoptosis in several prostate cancer cell lines. ⺠Suppressor of cytokine signalling-3 is expressed in prostate cancer. ⺠Antibody CNTO 328 (Anti IL-6) was tested in preclinical research and clinical trials.
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Authors
Zoran Culig, Martin Puhr,