Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8477701 | Molecular and Cellular Endocrinology | 2012 | 7 Pages |
Abstract
⺠Molecular diversity of cAMP signalling molecules reviewed. ⺠Detection of cAMP with genetically engineered biosensors has provided a flurry of new information. ⺠cAMP synthesis may occur at intracellular sites by endocytosed receptor-G protein-adenylyl cyclase complexes. ⺠Preassembled receptor-G protein-adenylyl cyclase complexes are found intracellularly and may be clinically relevant. ⺠Hypothetical model of regenerative intracellular cAMP signal propagation is presented.
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Authors
Ferenc A. Antoni,