| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477711 | Molecular and Cellular Endocrinology | 2012 | 7 Pages |
Abstract
⺠TRESK is a K2P potassium channel regulated by cytoplasmic Ca2+ concentration. ⺠The calcium/calmodulin-regulated phosphatase calcineurin activates the channel. ⺠TRESK is primarily expressed in the sensory neurons of DRG and trigeminal ganglia. ⺠Dominant negative mutation of the human channel is linked to migraine with aura. ⺠TRESK has a role in the trigeminovascular system or in cortical spreading depression.
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Authors
Péter Enyedi, Gabriella Braun, Gábor Czirják,