| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477716 | Molecular and Cellular Endocrinology | 2012 | 8 Pages |
Abstract
⺠Regulation of mitochondrial Ca2+ uptake is elusive. ⺠We review the role of p38MAPK/nPKC isoforms and Mg2+ in the control of Ca2+ uptake. ⺠We study the effect of these kinases on aldosterone production. ⺠Attenuation of mitochondrial Ca2+ uptake reduces aldosterone secretion.
Keywords
TNFαnPKCH295RYFPAIIFCCPIP3PDDPDIGFPopa1inositol 1,4,5-trisphosphatePMAMg2+p38 MAPK[Ca2+]c[Ca2+]maldosteroneAngiotensin IItruncated Bidtumor necrosis factor αCa2+ signalingendoplasmic reticulumPlasma membranephorbol myristyl acetateMitochondriaMitochondrial membrane potentialprotein disulfide isomeraseyellow fluorescent proteingreen fluorescent proteinΨmcarbonyl cyanide-p-trifluoromethoxyphenylhydrazone
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Authors
Gergö Szanda, Anikó Rajki, András Spät,