Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8477720 | Molecular and Cellular Endocrinology | 2012 | 14 Pages |
Abstract
⺠Mitochondrial Ca2+ sequestration was tested by various techniques. ⺠Kinetics and Ca2+ sensitivity of mitochondrial Ca2+ uptake depends on the techniques chosen. ⺠By electrophysiology, 2 and 3 distinct Ca2+ inward currents were measured in HeLa and endothelial cell mitoplasts. ⺠Mitoplast Ca2+ inward currents differ in frequency of appearance and conductance ranging from 7.6 to 74.3 pS. ⺠Mitochondrial Ca2+ uptake routes/modes exists and might be cell specific.
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Authors
Claire Jean-Quartier, Alexander I. Bondarenko, Muhammad Rizwan Alam, Michael Trenker, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier,