Article ID Journal Published Year Pages File Type
8477729 Molecular and Cellular Endocrinology 2012 8 Pages PDF
Abstract
► Genomics and mouse models shed light on the role of AR gene variation in cancer. ► AR's polymorphic glutamine tract influences prostate cancer progression in mice. ► AR somatic mutations identify multiple mechanisms and pathways to evade therapy. ► Targeting interacting partners identified by mutant ARs may combat resistance.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
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