| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8477750 | Molecular and Cellular Endocrinology | 2011 | 10 Pages |
Abstract
⺠We analyzed the effects of sustained castration on epididymal white adipose tissue (WAT) in C57BL/6J mice which were fed a regular or high-fat diet. ⺠Castration has profound effects on WAT morphology (smaller adipocytes and increased stromal cell compartment) and function. ⺠Castration reduces WAT wet weight and WAT wet weight/body weight ratio. ⺠Serum leptin levels are reduced after castration independent of diet; changes in adiponectin and resistin were diet-dependent. ⺠Castration induces specific chemokines and cytokines in WAT.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Daniel Floryk, Shinji Kurosaka, Ryuta Tanimoto, Guang Yang, Alexei Goltsov, Sanghee Park, Timothy C. Thompson,