Article ID Journal Published Year Pages File Type
8477753 Molecular and Cellular Endocrinology 2011 11 Pages PDF
Abstract
► We investigated how estrogen inhibited the proliferation of pituitary lactotrophs. ► DNA microarray analysis identified Bcl3 as an estrogen-downregulated gene. ► Overexpression of Bcl3 blocked the antiproliferative action of estrogen. ► Bcl3 is implicated in the antiproliferative action of estrogen on lactotrophs.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
Inhibition of Bcl3 gene expression mediates the anti-proliferative action of estrogen in pituitary lactotrophs in primary culture
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