Article ID Journal Published Year Pages File Type
8477833 Molecular and Cellular Endocrinology 2011 6 Pages PDF
Abstract
► In preadipocytes IR, IGF-IR and insulin/IGF-I hybrid receptors were detected. ► Insulin and IGF-I activate their cognate receptors and IGF-I also hybrid receptors. ► IGF-II activates IR, IGF-IR and insulin/IGF-I hybrid receptors. ► Insulin and IGF-I are partial agonists to each other's receptors.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
Differential effects of IGF-I, IGF-II and insulin in human preadipocytes and adipocytes - Role of insulin and IGF-I receptors
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