Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8478389 | Molecular and Cellular Neuroscience | 2018 | 22 Pages |
Abstract
In conclusion, each of the MAPKs showed a specific spatio-temporal expression and activation pattern in the retina, ONH and optic nerve as a result of IOP elevation. These findings likely reflect the roles of the individual enzymes, and the cells in which they reside, in the developing pathology following IOP elevation. These data have implications for understanding the mechanisms of ocular pathology in diseases such as glaucoma.
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Authors
Teresa Mammone, Glyn Chidlow, Robert J. Casson, John P.M. Wood,