Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8479829 | Seminars in Cell & Developmental Biology | 2018 | 26 Pages |
Abstract
The cell membrane, involved in almost all communications of cells and surrounding matrix, is one of the most complicated components of cells. Lack of suitable methods for the detection of cell membranes in vivo has sparked debates on the biochemical composition and structure of cell membranes over half a century. The development of single molecule techniques, such as AFM, SMFS, and TREC, provides a versatile platform for imaging and manipulating cell membranes in biological relevant environments. Here, we discuss the latest developments in AFM and the progress made in cell membrane research. In particular, we highlight novel structure models and dynamic processes, including the mechanical properties of the cell membranes.
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Authors
Yan Shi, Mingjun Cai, Lulu Zhou, Hongda Wang,