Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8480099 | Seminars in Cell & Developmental Biology | 2016 | 29 Pages |
Abstract
Fibroblast growth factors are potent morphogens and mitogens that are highly conserved among the animal kingdom. These growth factors play key roles in organogenesis during embryonic development as well as homeostatic balance during postnatal life. In this review, we provide a summary about the current knowledge regarding the involvement of fibroblast growth factor signaling in organ regeneration and repair. We also shed light on the use of these growth factors in previous and current clinical trials in a wide array of human diseases.
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Authors
Elie El Agha, Djuro Kosanovic, Ralph T. Schermuly, Saverio Bellusci,