Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8480241 | Seminars in Cell & Developmental Biology | 2016 | 10 Pages |
Abstract
- Limb develops along proximal-distal-PD, anterior-posterior-AP & dorsal-ventral axes.
- The Integrated Space-Time model for coordinated PD/AP limb patterning is proposed.
- Limb molecular clock gene hairy2 is a crucial component of limb development.
- Feedback signaling module with self-terminating property terminates limb outgrowth.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Caroline J. Sheeba, Raquel P. Andrade, Isabel Palmeirim,