| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8480324 | Seminars in Cell & Developmental Biology | 2015 | 4 Pages |
Abstract
Epigenetic variation, a stable alteration in gene expression, occurs at multiple moments during development. Several instances of non-Mendelian transmission to the progenies modes are very intriguing. Studies of the mode of hereditary transmission revealed in a series of such cases a role of noncoding RNA molecules as inducers. While still an enigmatic mechanism, emerging models pinpoint to a more general roles of these variations, initiated as a response to genetic and environmental variation. Here we compare the known modes of transgenerational epigenetic variation in mice and humans.
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Authors
Minoo Rassoulzadegan, François Cuzin,