Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8480425 | Seminars in Cell & Developmental Biology | 2015 | 9 Pages |
Abstract
- Extracellular vesicles are increasingly recognised players of intercellular communication.
- Most frequently studied posttranslational modifications include glycosylation, phosphorylation, oxidation and citrullination.
- Posttranslational modifications have major impact on vesicle biogenesis, cargo sorting and vesicular uptake.
- Enzymes capable of carrying out posttranslational modifications are transported by extracellular vesicles.
- Characteristic posttranslational modifications of extracellular vesicle proteins may associate with specific pathophysiological processes.
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Authors
Katalin Szabó-Taylor, Brent Ryan, Xabier Osteikoetxea, Tamás G. Szabó, Barbara Sódar, Marcsilla Holub, Andrea Németh, Krisztina Pálóczi, Ãva Pállinger, Paul Winyard, Edit I. Buzás,