Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8480680 | Seminars in Cell & Developmental Biology | 2014 | 9 Pages |
Abstract
Decapentaplegic (Dpp), the fly homolog of the secreted mammalian BMP2/4 signaling molecules, is involved in almost all aspects of fly development. Dpp has critical functions at all developmental stages, from patterning of the eggshell to the determination of adult intestinal stem cell identity. Here, we focus on recent findings regarding the transcriptional regulatory logic of the pathway, on a new feedback regulator, Pentagone, and on Dpp's roles in scaling and growth of the Drosophila wing.
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Authors
Fisun Hamaratoglu, Markus Affolter, George Pyrowolakis,