| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8480743 | Seminars in Cell & Developmental Biology | 2014 | 40 Pages |
Abstract
- DNA replication is asymmetric, bidirectional, semi-discontinuous and semi-conservative.
- In eukaryotes, DNA is organized as heritable euchromatin or heterochromatin structures with specific histone modifications.
- The inheritance of these stable epigenetic states of chromatin is coupled to DNA replication.
- Asymmetric cell division during developmental switches is coupled to asymmetry of DNA replication.
- Chromatin remodeling/assembly factors interact with DNA replication factors to propagate the epigenetic chromatin states.
Keywords
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Authors
Jagmohan Singh,