Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8480753 | Seminars in Cell & Developmental Biology | 2014 | 7 Pages |
Abstract
- DNA replication, development, pluripotency and cancer share common regulatory nodes.
- Several pre-replicative machinery proteins have developmental roles.
- Deregulated expression of pre-RC members can induce carcinogenesis.
- Pluripotency-associated transcription factors influence DNA replication.
- Overexpression of pluripotency-associated transcription factors is linked to cancer.
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Authors
S. Champeris Tsaniras, N. Kanellakis, I.E. Symeonidou, P. Nikolopoulou, Z. Lygerou, S. Taraviras,