Article ID Journal Published Year Pages File Type
8480753 Seminars in Cell & Developmental Biology 2014 7 Pages PDF
Abstract

- DNA replication, development, pluripotency and cancer share common regulatory nodes.
- Several pre-replicative machinery proteins have developmental roles.
- Deregulated expression of pre-RC members can induce carcinogenesis.
- Pluripotency-associated transcription factors influence DNA replication.
- Overexpression of pluripotency-associated transcription factors is linked to cancer.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
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